Vitronectin Recombinant Protein

• Catalog number
  40-534
• Price
  Please ask
• Size
  0.1 mg, 0.5 mg

• About recombinant protein
  Vitronectin is a secreted glycoprotein which is synthesized in the liver. It circulates primarily in monomeric form, but can undergo conformational change to a structure that forms disulfide linked multimers. The multimeric Vitronectin can efficiently bind to and incorporate into the extracellular matrix. Within the matrix, Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Additionally, recombinant vitronectin can function as a chemically defined matrix component in human embryonic stem cell renewal media. Recombinant human Vitronectin is a 459 amino acid single chain monomeric protein, which migrates at an apparent molecular weight of 75 kDa by SDS-PAGE under reducing conditions.
• Other name of the recombinant
  VN, V75, VNT, Vitronectin, S-protein, VN
• Recombinant in
  HEK293 cells
• SEQUENCE
  DQESCKGRCT EGFNVDKKCQ CDELCSYYQS CCTDYTAECK PQVTRGDVFT MPEDEYTVYD DGEEKNNATV HEQVGGPSLT SDLQAQSKGN PEQTPVLKPE EEAPAPEVGA SKPEGIDSRP ETLHPGRPQP PAEEELCSGK PFDAFTDLKN GSLFAFRGQY CYELDEKAVR PGYPKLIRDV WGIEGPIDAA FTRINCQGKT YLFKGSQYWR FEDGVLDPDY PRNISDGFDG IPDNVDAALA LPAHSYSGRE RVYFFKGKQY WEYQFQHQPS QEECEGSSLS AVFEHFAMMQ RDSWEDIFEL LFWGRTSAGT RQPQFISRDW HGVPGQVDAA MAGRIYISGM APRPSLAKKQ RFRHRNRKGY RSQRGHSRGR NQNSRRPSRA TWLSLFSSEE SNLGANNYDD YRMDWLVPAT CEPIQSVFFF SGDKYYRVNL RTRRVDTVDP PYPRSIAQYW LGCPAPGHL
• Activity
  Endotoxin level is less than 0.1 ng per ug (1EU/μg).
• Keep at
  The lyophilized Vitronectin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Vitronectin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Vitronectin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  88853069
• Accession nr
  NP_000629.3
• Pureity
  Greater than or equal to 95% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  7448
• Gene name
  vitronectin
• Source
  Homo sapiens
• Uniprot
  P04004
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Vitronectin   Protein  
• Gene symbol
  VTN
• Short name
  Vitronectin Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Vitronectin Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12724
• Gene
  VTN
• Long gene name
  vitronectin
• Synonyms gene name
  • vitronectin (serum spreading factor, somatomedin B, complement S-protein)
• Synonyms
  • VN
• Synonyms name
  • serum spreading factor
  • somatomedin B
  • complement S-protein
• GenBank acession
  • BC005046
• Locus
  17q11.2
• Discovery year
  1992-07-30
• Entrez gene record
  7448
• Pubmed identfication
  • 2447940
• RefSeq identity
  • NM_000638
• Classification
  • Complement system regulators and receptors
  • Receptor ligands
• VEGA ID
  OTTHUMG00000132500

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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