Trefoil Factor 1 Recombinant Protein
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Catalog number
40-292
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Price
Please ask
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Size
0.005 mg, 0.02 mg
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About recombinant protein
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene. Recombinant human TFF1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
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Other name of the recombinant
pS2, BCEI, HPS2, HP1.A, pNR-2, D21S21, PS2, Trefoil factor 1, Breast cancer estrogen-inducible protein
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Recombinant in
E. coli
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SEQUENCE
EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF
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Activity
Biological activity was determined by its ability to chemoattract human MCF - 7 cells using a concentration 5 - 10 μg/mL.
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Keep at
The lyophilized Trefoil Factor 1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Trefoil Factor 1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Trefoil Factor 1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
4507451
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Accession nr
NP_003216.1
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Pureity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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About
This product is for research use only.
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Protein s origin
Human
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Vial
Lyophilized
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NCBI ID
7031
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Gene name
trefoil factor 1
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Source
Homo sapiens
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Uniprot
P04155
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TFF1
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Short name
Trefoil Factor 1 Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Trefoil Factor 1 Rec. Protein
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
trefoil factor 1
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Synonyms gene
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Synonyms gene name
- breast cancer, estrogen-inducible sequence expressed in
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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