TGF-alpha Recombinant Protein

• Catalog number
  40-117
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• About recombinant protein
  TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
• Other name of the recombinant
  TFGA, Protransforming growth factor alpha, EGF-like TGF, TGF-alpha
• Recombinant in
  E. coli
• SEQUENCE
  VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
• Activity
  The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 106 units/mg.
• Keep at
  The lyophilized TGF-alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted TGF-alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing TGF-alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  153791414
• Accession nr
  NP_001093161.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  7039
• Gene name
  transforming growth factor, alpha
• Source
  Homo sapiens
• Uniprot
  P01135
• Pictures of recombinant
• Rec pdf
• Description
  The TGF-alpha Recombinant Protein is a α- or alpha protein sometimes glycoprotein present in blood.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  TGF-alpha   Protein  
• Gene symbol
  TGFA
• Short name
  TGF-alpha Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  TGF-a Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:11765
• Gene
  TGFA
• Long gene name
  transforming growth factor alpha
• Synonyms gene name
  • transforming growth factor, alpha
• Locus
  2p13.3
• Discovery year
  2001-06-22
• Entrez gene record
  7039
• Pubmed identfication
  • 3459638
  • 10552925
• VEGA ID
  OTTHUMG00000129669

Gene info

• Identity
  HGNC:41389
• Gene
  TGFA-IT1
• Long gene name
  TGFA intronic transcript 1
• Synonyms gene name
  • TGFA intronic transcript 1 (non-protein coding)
• Locus
  2p13.3
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000153490

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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