sCD34 Recombinant Protein
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Catalog number
40-570
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Price
Please ask
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Size
0.005 mg, 0.02 mg
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About recombinant protein
CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein.
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Other name of the recombinant
Hematopoietic progenitor cell antigen CD34
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Recombinant in
CHO cells
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SEQUENCE
LDNNGTATPE LPTQGTFSNV STNVSYQETT TPSTLGSTSL HPVSQHGNEA TTNITETTVK FTSTSVITSV YGNTNSSVQS QTSVISTVFT TPANVSTPET TLKPSLSPGN VSDLSTTSTS LATSPTKPYT SSSPILSDIK AEIKCSGIRE VKLTQGICLE QNKTSSCAEF KKDRGEGLAR VLCGEEQADA DAGAQVCSLL LAQSEVRPQC LLLVLANRTE ISSKLQLMKK HQSDLKKLGI LDFTEQDVAS HQSYSQKT
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Activity
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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Keep at
The lyophilized sCD34 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted sCD34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing sCD34 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
68342038
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Accession nr
NP_001020280.1
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Pureity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
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About
This product is for research use only.
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Protein s origin
Human
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Vial
Lyophilized
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NCBI ID
947
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Gene name
CD34 molecule
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Source
Homo sapiens
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Uniprot
P28906
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD34
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Short name
sCD34 Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
sCD34 Rec. Protein
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
CD34 molecule
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Synonyms gene name
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GenBank acession
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Locus
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Discovery year
1990-09-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Removal of bone marrow and evaluation of its histologic picture.
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Tree numbers
- E01.370.225.625.135
- E05.200.625.135
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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