NT-4 Recombinant Protein

• Catalog number
  40-498
• Price
  Please ask
• Size
  0.002 mg, 0.01 mg

• About recombinant protein
  NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
• Other name of the recombinant
  NT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5, Neurotrophin-4, Neurotrophin-5
• Recombinant in
  E. coli
• SEQUENCE
  GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
• Activity
  Biological activity was determined by the dose - dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20 - 50 ng/mL.
• Keep at
  The lyophilized NT-4 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted NT-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing NT-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  5453808
• Accession nr
  NP_006170.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  4909
• Gene name
  neurotrophin 4
• Source
  Homo sapiens
• Uniprot
  P34130
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NT-4   Protein  
• Gene symbol
  NTF4
• Short name
  NT-4 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  NT-4 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8024
• Gene
  NTF4
• Long gene name
  neurotrophin 4
• Synonyms gene
  • NTF5
• Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
• Synonyms
  • NT-4/5
  • GLC1O
• Synonyms name
  • neurotrophic factor 4
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4909
• Pubmed identfication
  • 1496419
• RefSeq identity
  • NM_006179
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000191728

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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