IL-31 Recombinant Protein

  • Catalog number
    40-428
  • Price
    Please ask
  • Size
    0.002 mg, 0.01 mg
  • About recombinant protein
    IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.
  • Other name of the recombinant
    1700013B14Rik, Interleukin-31, IL-31
  • Recombinant in
    E. coli
  • SEQUENCE
    MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
  • Keep at
    The lyophilized IL-31 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-31 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
  • Rec PROTEIN GI
    247301073
  • Accession nr
    NP_083870.1
  • Pureity
    Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
  • About
    This product is for research use only.
  • Protein s origin
    Murine
  • Vial
    Lyophilized
  • NCBI ID
    76399
  • Gene name
    interleukin 31
  • Source
    Mus musculus
  • Uniprot
    Q6EAL8
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    IL-31   Protein  
  • Gene symbol
    Il31
  • Short name
    IL-31 Recombinant Protein
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    Interleukin-31 Rec. Protein
  • Alternative technique
    rec
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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