IL-31 Recombinant Protein
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Catalog number
40-428
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Price
Please ask
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Size
0.002 mg, 0.01 mg
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About recombinant protein
IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.
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Other name of the recombinant
1700013B14Rik, Interleukin-31, IL-31
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Recombinant in
E. coli
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SEQUENCE
MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
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Keep at
The lyophilized IL-31 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-31 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
247301073
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Accession nr
NP_083870.1
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Pureity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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About
This product is for research use only.
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Protein s origin
Murine
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Vial
Lyophilized
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NCBI ID
76399
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Gene name
interleukin 31
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Source
Mus musculus
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Uniprot
Q6EAL8
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
Il31
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Short name
IL-31 Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Interleukin-31 Rec. Protein
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
interleukin 31
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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