IL-3 Recombinant Protein

• Catalog number
  40-601
• Price
  Please ask
• Size
  0.01 mg

• About recombinant protein
  IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. .
• Other name of the recombinant
  IL-3, MCGF, MULTI-CSF, Interleukin-3, Hematopoietic growth factor, IL-3
• Recombinant in
  E. coli
• His tag on the recombinant protein
  no His tag
• SEQUENCE
  APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
• Activity
  The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is = 0.1 ng/mL, corresponding to a specific activity of = 1 x 107 units/mg.
• Keep at
  The lyophilized IL-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  28416915
• Accession nr
  NP_000579.2
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  3562
• Gene name
  interleukin 3 (colony-stimulating factor, multiple)
• Source
  Homo sapiens
• Uniprot
  P08700
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-3   Protein  
• Gene symbol
  IL3
• Short name
  IL-3 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-3 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6011
• Gene
  IL3
• Long gene name
  interleukin 3
• Synonyms gene name
  • interleukin 3 (colony-stimulating factor, multiple)
• Synonyms
  • IL-3
  • MULTI-CSF
  • MCGF
  • MGC79398
  • MGC79399
• Synonyms name
  • multilineage-colony-stimulating factor
  • hematopoietic growth factor
  • P-cell stimulating factor
  • mast-cell growth factor
  • colony-stimulating factor, multiple
• GenBank acession
  • M14743
• Locus
  5q31.1
• Discovery year
  2001-06-22
• Entrez gene record
  3562
• Pubmed identfication
  • 3489530
• RefSeq identity
  • NM_000588
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000059640

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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