IL-2 Recombinant Protein

• Catalog number
  40-599
• Price
  Please ask
• Size
  0.05 mg

• About recombinant protein
  IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. .
• Other name of the recombinant
  IL-2, TCGF, lymphokine, Interleukin-2, T-cell growth factor, IL-2
• Recombinant in
  E. coli
• His tag on the recombinant protein
  no His tag
• SEQUENCE
  MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
• Activity
  The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is = 0.1 ng/mL, corresponding to a specific activity of = 1 x 107 units/mg.
• Keep at
  The lyophilized IL-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  28178861
• Accession nr
  NP_000577.2
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  3558
• Gene name
  interleukin 2
• Source
  Homo sapiens
• Uniprot
  P60568
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-2   Protein  
• Gene symbol
  IL2
• Short name
  IL-2 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-2 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6001
• Gene
  IL2
• Long gene name
  interleukin 2
• Synonyms
  • IL-2
  • TCGF
• Synonyms name
  • T cell growth factor
• GenBank acession
  • U25676
• Locus
  4q27
• Discovery year
  1986-01-01
• Entrez gene record
  3558
• Pubmed identfication
  • 3260003
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000133075

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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