IL-15 Recombinant Protein

• Catalog number
  40-422
• Price
  Please ask
• Size
  0.002 mg, 0.01 mg

• About recombinant protein
  IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.
• Other name of the recombinant
  IL-15, AI503618, Interleukin-15, IL-15
• Recombinant in
  E. coli
• SEQUENCE
  MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS
• Activity
  The ED50 was determined by the stimulation of the proliferation of murine CTLL - 2 cells is < 5.0 ng/mL, corresponding to a specific activity of > 2 x 105 units/mg.
• Keep at
  The lyophilized IL-15 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-15 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-15 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  363000984
• Accession nr
  NP_001241676.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Murine
• Vial
  Lyophilized
• NCBI ID
  16168
• Gene name
  interleukin 15
• Source
  Mus musculus
• Uniprot
  P48346
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-15   Protein  
• Gene symbol
  Il15
• Short name
  IL-15 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-15 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:5977
• Gene
  IL15
• Long gene name
  interleukin 15
• Synonyms
  • IL-15
  • MGC9721
• GenBank acession
  • U14407
• Locus
  4q31.21
• Discovery year
  1994-07-11
• Entrez gene record
  3600
• Pubmed identfication
  • 8178155
• RefSeq identity
  • NM_172175
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000133418

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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