CTGFL Recombinant Protein

• Catalog number
  40-215
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.
• Other name of the recombinant
  CCN5, CT58, CTGF-L, CCN5, CTGFL, UNQ228/PRO261, WNT1-inducible-signaling pathway protein 2, CCN family member 5, WISP-2
• Recombinant in
  E. coli
• SEQUENCE
  MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
• Activity
  The ED50 was determined by its ability to inhibit IGF - II induced proliferation of MCF - 7 is between 10 - 20 ng/mL in the presence of 15 ng/mL of human IGF - II.
• Keep at
  The lyophilized CTGFL recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted CTGFL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing CTGFL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  4507923
• Accession nr
  NP_003872.1
• Pureity
  Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  8839
• Gene name
  WNT1 inducible signaling pathway protein 2
• Source
  Homo sapiens
• Uniprot
  O76076
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CTGFL   Protein  
• Gene symbol
  WISP2
• Short name
  CTGFL Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  CTGFL Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12770
• Gene
  CCN5
• Long gene name
  cellular communication network factor 5
• Synonyms gene
  • WISP2
• Synonyms gene name
  • WNT1 inducible signaling pathway protein 2
• Synonyms
  • CT58
  • CTGF-L
  • WISP-2
• GenBank acession
  • AF100780
• Locus
  20q13.12
• Discovery year
  1999-01-22
• Entrez gene record
  8839
• Pubmed identfication
  • 9843955
• RefSeq identity
  • NM_003881
• Classification
  • Cellular communication network factors
• VEGA ID
  OTTHUMG00000033071

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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