anti-ZMPSTE24 Antibody
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Catalog number30-216
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PricePlease ask
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Size50 ug
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Gene infoZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
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Gene namesZMPSTE24, FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZMPSTE24.
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Immuno applicationELISA, Western Blot
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Antibody adviceZMPSTE24 antibody can be used for detection of ZMPSTE24 by ELISA at 1:312500. ZMPSTE24 antibody can be used for detection of ZMPSTE24 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store ZMPSTE24 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr18379366
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Ncbi nrNP_005848
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KDa55 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr10269
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GENE symbolZMPSTE24
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Antigene namezinc metallopeptidase STE24
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SourceHomo sapiens
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Protein nrO75844
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolZMPSTE24-DT, ZMPSTE24
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Short nameanti-ZMPSTE24 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toZMPSTE24 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameZMPSTE24 divergent transcript
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Locus
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Discovery year2021-01-06
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namezinc metallopeptidase STE24
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Synonyms gene name
- zinc metalloproteinase (STE24 homolog, yeast)
- zinc metallopeptidase (STE24 homolog, yeast)
- zinc metallopeptidase STE24 homolog (S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-17
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Entrez gene record
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Pubmed identfication
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Classification
- M48 metallopeptidase family
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
