anti-VASH1 Antibody
-
Catalog number6325
-
PricePlease ask
-
Size0.02 mg, 0.1 mg
-
-
Gene infoVASH1 Antibody: VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development. VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2). The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis. Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.
-
Gene namesVASH1 Antibody: KIAA1036, KIAA1036, VASH, Vasohibin-1
-
Antibodie s labelunlabelled serum
-
PurityVASH1 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
Spicific toVASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist; this antibody will recognize only the long isoform.
-
AntigenVASH1 antibody was made against a 19 amino acid synthetic peptide near the carboxy terminus of human VASH1.
-
Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
-
Antibody adviceVASH1 antibody can be used for detection of VASH1 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
-
Suspention pH azideVASH1 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atVASH1 antibody can be stored at 4 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works withHuman, Mouse, Rat
-
Omim nr7662454
-
Ncbi nrNP_055724
-
Vial with antibodyin solution
-
Quantity per ml1 mg/mL
-
NCBI GENE nr22846
-
GENE symbolVASH1
-
Antigene namevasohibin 1
-
SourceHomo sapiens
-
Protein nrQ7L8A9
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolVASH1-DT, VASH1-AS1, VASH1
-
Short nameanti-VASH1 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toVASH1 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameVASH1 divergent transcript
-
Locus
-
Discovery year2021-01-14
-
Classification
- Divergent transcripts
Gene info
-
Identity
-
Gene
-
Long gene nameVASH1 antisense RNA 1
-
Locus
-
Discovery year2017-03-21
-
Entrez gene record
-
RefSeq identity
-
Classification
- Antisense RNAs
Gene info
-
Identity
-
Gene
-
Long gene namevasohibin 1
-
Synonyms gene
-
Synonyms gene name
- KIAA1036
-
GenBank acession
-
Locus
-
Discovery year2003-11-21
-
Entrez gene record
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
