anti-TRPC6 Antibody

• Catalog number
  3897
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TRPC6 Antibody: The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. When expressed in transfected cells, TRPC6 acts as a non-selective store-independent receptor-activated cation channel. It is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation. There is increasing evidence that TRPC6 encodes endogenous DAG-activated receptor-operated cation channels in vivo.
• Gene names
  TRPC6 Antibody: TRP6, FSGS2, TRP6, Short transient receptor potential channel 6, Transient receptor protein 6, TrpC6
• Antibodie s label
  unlabelled serum
• Purity
  TRPC6 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  This antibody may cross-react with TRPC3.
• Antigen
  TRPC6 antibody was made against a 14 amino acid synthetic peptide from near the carboxy terminus of human TRPC6.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TRPC6 antibody can be used for the detection of TRPC6 by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TRPC6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TRPC6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  62739910
• Ncbi nr
  AAH93658
• KDa
  Predicted: 100, 102 kDa Observed: 93 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7225
• GENE symbol
  TRPC6
• Antigene name
  transient receptor potential cation channel, subfamily C, member 6
• Source
  Homo sapiens
• Protein nr
  Q9Y210
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRPC6  
• Gene symbol
  TRPC6
• Short name
  anti-TRPC6 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTRPC6 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12338
• Gene
  TRPC6
• Long gene name
  transient receptor potential cation channel subfamily C member 6
• Synonyms gene
  • FSGS2
• Synonyms gene name
  • focal segmental glomerulosclerosis 2
  • transient receptor potential cation channel, subfamily C, member 6
• Synonyms
  • TRP6
• GenBank acession
  • AJ006276
• Locus
  11q22.1
• Discovery year
  1998-08-05
• Entrez gene record
  7225
• Pubmed identfication
  • 9925922
  • 16382100
  • 15879175
• RefSeq identity
  • NM_004621
• Classification
  • MicroRNA protein coding host genes
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000167483

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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