anti-TRIP12 Antibody

• Catalog number
  7953
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner (1). TRIP12 (thyroid hormone receptor interactor 12) is an ATP-dependent E3 ubiquitin ligase involved in the human ubiquitin fusion degradation (UFD) pathway and also modulates the NEDD8 pathway (2,3). TRIP12 contains one WWE domain and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain suggested to contain a noncovalent ubiquitin-binding site (4). TRIP12 acts as a key regulator of DNA damage response and the ubiquitin ligase activity of TRIP12 is essential for mouse development (5).
• Gene names
  TRIP12 Antibody: ULF, TRIP-12, KIAA0045, ULF, E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf
• Antibodie s label
  unlabelled serum
• Purity
  TRIP12 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  TRIP12 antibody is human, mouse and rat reactive. At least four isoforms are known to exist.
• Antigen
  TRIP12 antibody was made against a 18 amino acid peptide near the carboxy terminus of human TRIP12.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TRIP12 antibody can be used for detection of TRIP12 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TRIP12 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TRIP12 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  10863903
• Ncbi nr
  NP_004229
• KDa
  Predicted: 219 kDa Observed: 220 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9320
• GENE symbol
  TRIP12
• Antigene name
  Thyroid hormone receptor interactor 12
• Source
  homo sapiens
• Protein nr
  Q14669
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRIP12  
• Gene symbol
  TRIP12
• Short name
  anti-TRIP12 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody tothyroid hormone receptor interactor 12 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  thyroid hormone receptor interactor 12, TRIP-12 and ULF, TRIP12 and IDBG-82749 and ENSG00000153827 and 9320, thyroid hormone receptor binding, nuclei, Trip12 and IDBG-174830 and ENSMUSG00000026219 and 14897, TRIP12 and IDBG-644297 and ENSBTAG00000021653 and 514387

Gene info

• Identity
  HGNC:12306
• Gene
  TRIP12
• Long gene name
  thyroid hormone receptor interactor 12
• Synonyms
  • KIAA0045
  • ULF
  • TRIPC
• Synonyms name
  • E3 ubiquitin-protein ligase for Arf
• GenBank acession
  • L40383
• Locus
  2q36.3
• Discovery year
  1999-03-19
• Entrez gene record
  9320
• Pubmed identfication
  • 7776974
  • 27800609
  • 28251352
• RefSeq identity
  • NM_004238
• Classification
  • Armadillo like helical domain containing
  • HECT domain containing
• VEGA ID
  OTTHUMG00000153623

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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