anti-Transthyretin Antibody
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Catalog number
5157
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.
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Gene names
Transthyretin Antibody: CTS, CTS1, PALB, TBPA, HEL111, HsT2651, Transthyretin, ATTR
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Antibodie s label
unlabelled serum
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Purity
Transthyretin Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Chicken
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Type
Polyclonal
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Immunoglobulin
IgY
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Antigen
Transthyretin antibody was made against a 17 amino acid synthetic peptide near the center of human Transthyretin.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
Transthyretin antibody can be used for detection of Transthyretin by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
Transthyretin Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Transthyretin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
136464
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Ncbi nr
P02766
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
7276
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GENE symbol
TTR
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Antigene name
transthyretin
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Source
Homo sapiens
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Protein nr
P02766
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
TTR
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Short name
anti-Transthyretin Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toTransthyretin (antibody to-)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
transthyretin
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Synonyms gene
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Synonyms gene name
- prealbumin, amyloidosis type I
- carpal tunnel syndrome 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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