anti-TOR Antibody

• Catalog number
  3485
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TOR Antibody: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. It was initially discovered as a kinase whose ability to stimulate T cell proliferation in response to IL-2 could be inhibited by the immunosuppressive drug rapamycin. Rapamycin inhibits TOR in other cell types resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with the regulatory proteins RAPTOR and GbetaL. Its downstream targets are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs). Regulation of these protein families allows TOR to control protein biosynthesis.
• Gene names
  TOR Antibody: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, FRAP, FK506-binding protein 12-rapamycin complex-associated protein 1, mTOR
• Antibodie s label
  unlabelled serum
• Purity
  TOR Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TOR antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human TOR.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  TOR antibody can be used for the detection of TOR by Western blot at 1 to 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL.
• Suspention pH azide
  TOR Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TOR antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  4826730
• Ncbi nr
  NP_004949
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  2475
• GENE symbol
  FRAP1
• Antigene name
  FK506 binding protein 12-rapamycin associated protein 1
• Source
  Homo sapiens
• Protein nr
  P42345
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TOR  
• Gene symbol
  RORC
• Short name
  anti-TOR Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTOR (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10260
• Gene
  RORC
• Long gene name
  RAR related orphan receptor C
• Synonyms gene name
  • RAR-related orphan receptor C
• Synonyms
  • RZRG
  • RORG
  • NR1F3
  • TOR
• GenBank acession
  • U16997
• Locus
  1q21
• Discovery year
  1995-04-13
• Pubmed identfication
  • 7811290
• Classification
  • RAR related orphan receptors
• VEGA ID
  OTTHUMG00000013053
• Locus Specific Databases
  • LRG_1322

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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