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Gene info
TNFSF4 Antibody: The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNγ. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
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Gene names
TNFSF4 Antibody: GP34, CD252, OX4OL, TXGP1, CD134L, OX-40L, Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40L
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Antibodie s label
unlabelled serum
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Purity
TNFSF4 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Spicific to
At least two isoforms of TNFSF4 are known to exist; this antibody will detect both isoforms.
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Antigen
Rabbit polyclonal TNFSF4 antibody was made against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
TNFSF4 antibody can be used for detection of TNFSF4 by Western blot at 0.5 - 1 ug/mL.
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Suspention pH azide
TNFSF4 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
TNFSF4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works with
Human, Mouse, Rat
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Omim nr
4507603
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Ncbi nr
NP_003317
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KDa
20 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
7292
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GENE symbol
TNFSF4
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Antigene name
tumor necrosis factor (ligand) superfamily, member 4
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Source
homo sapiens
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Protein nr
P23510
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
TNFSF4
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Short name
anti-TNFSF4 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody totumor necrosis factor (ligand) superfamily, member 4 (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
tumor necrosis factor (ligand) superfamily, member 4, CD134L and CD252 and GP34 and OX-40L and OX4OL and TXGP1, TNFSF4 and IDBG-104864 and ENSG00000117586 and 7292, tumor necrosis factor receptor superfamily binding, Extracellular, Tnfsf4 and IDBG-201525 and ENSMUSG00000026700 and 22164, TNFSF4 and IDBG-632319 and ENSBTAG00000002894 and 539800
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