anti-TEM2 Antibody

• Catalog number
  4363
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TEM2 Antibody: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
• Gene names
  TEM2 Antibody: Rhes, TEM2, MGC:4834, GTP-binding protein Rhes, Ras homolog enriched in striatum
• Antibodie s label
  unlabelled serum
• Purity
  TEM2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  TEM2 antibody may cross-react with the closely related protein RASD1.
• Antigen
  TEM2 antibody was made against a 16 amino acid synthetic peptide near the amino terminus of the human TEM2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TEM2 antibody can be used for detection of TEM2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TEM2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TEM2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  21362868
• Ncbi nr
  Q96D21
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  23551
• GENE symbol
  RASD2
• Antigene name
  RASD family, member 2
• Source
  Homo sapiens
• Protein nr
  Q96D21
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TEM2  
• Gene symbol
  RASD2
• Short name
  anti-TEM2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTEM2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18229
• Gene
  RASD2
• Long gene name
  RASD family member 2
• Synonyms gene name
  • RASD family, member 2
• Synonyms
  • TEM2
  • Rhes
  • MGC:4834
• Synonyms name
  • tumor endothelial marker 2
  • Ras homolog enriched in striatum
• GenBank acession
  • AF279143
• Locus
  22q12.3
• Discovery year
  2002-02-21
• Entrez gene record
  23551
• Pubmed identfication
  • 10947988
  • 10467249
  • 14724584
• RefSeq identity
  • NM_014310
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000150607

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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