anti-Tau (phospho Ser416) Antibody

• Catalog number
  50-270
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy. It has been well documented that hyperphosphorylated tau is a major component of paired helical filaments in AD brain (Lee 1995). Serine 416 has been demonstrated to be a major phosphorylation site in vitro by CaM kinase II (Steiner at al. 1990).
• Gene names
  pTau, Mtapt, RNPTAU, Tau, Neurofibrillary tangle protein, PHF-tau
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  Specific for ~59, 65, 68k tau protein phosphorylated at Ser416.
• Antigen
  Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser416 of rat tau.
• Immuno application
  Western Blot
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  Tau (Ser416) antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Bovine, Chicken
• Omim nr
  13432197
• Ncbi nr
  P19332
• KDa
  59/65/68
• Vial with antibody
  in solution
• NCBI GENE nr
  29477
• GENE symbol
  Mapt
• Antigene name
  microtubule-associated protein tau
• Source
  Rattus norvegicus
• Protein nr
  P19332
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Tau   phospho   Ser416  
• Short name
  anti-Tau (phospho Ser416) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTau (phosphorilated Ser416) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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