anti-Synapsin (phospho Ser549) Antibody
#
-
Catalog number50-239
-
Price:
-
Size0.1 mL
-
-
Gene infoSynapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.
-
Gene namesSynapsin I,
-
Antibodie s labelunlabelled serum
-
PurityAffinity Purified
-
Ab raised inRabbit
-
TypePolyclonal
-
AntigenPhosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of synapsin I.
-
Immuno applicationWestern Blot, immuno-histo-chemistry
-
Antibody adviceThe antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, non-human primate, bovine and canine tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
-
Suspention pH azide100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
-
Keep atSynapsin antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
-
Works withHuman, Mouse, Rat, Dog, Bovine
-
Omim nr1351166
-
Ncbi nrP17599
-
KDa78
-
Vial with antibodyin solution
-
NCBI GENE nr281510
-
GENE symbolSYN1
-
Antigene namesynapsin I
-
SourceBos taurus
-
Protein nrP17599
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Short nameanti-Synapsin (phospho Ser549) Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toSynapsin (phosphorilated Ser549) (antibody to-)
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data