anti-Strumpellin Antibody

• Catalog number
  6497
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Strumpellin Antibody: Strumpellin is a ubiquitously expressed, multi-transmembrane and spectrin-repeat-containing protein. It is named for Strumpell disease; a progressive upper-motor neurodegenerative disease termed hereditary spastic paraplegia (HSP). The Strumpellin gene maps to the eighth HSP locus (SPG8) on chromosome 8p24.13. Three families liked to this locus have mutations in the Strumpellin gene; rescue studies of zebrafish with decreased Strumpellin expression with Strumpellin mRNA containing these mutations showed impaired normal function of this protein. Recent studies suggest that Strumpellin may also be involved in protein aggregation diseases.
• Gene names
  Strumpellin Antibody: RTSC, SPG8, WASH complex subunit strumpellin
• Antibodie s label
  unlabelled serum
• Purity
  Strumpellin Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Multiple isoforms of Strumpellin are known to exist.
• Antigen
  Strumpellin antibody was made against a 19 amino acid synthetic peptide near the carboxy terminus of human Strumpellin.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  Strumpellin antibody can be used for detection of Strumpellin by Western blot at 1 ug/mL.
• Suspention pH azide
  Strumpellin Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Strumpellin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  120952851
• Ncbi nr
  NP_055661
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9897
• GENE symbol
  KIAA0196
• Antigene name
  KIAA0196
• Source
  Homo sapiens
• Protein nr
  Q12768
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Strumpellin  
• Gene symbol
  WASHC4, WASHC5
• Short name
  anti-Strumpellin Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toStrumpellin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29174
• Gene
  WASHC4
• Long gene name
  WASH complex subunit 4
• Synonyms gene
  • KIAA1033
• Synonyms gene name
  • KIAA1033
• Synonyms
  • SWIP
• Synonyms name
  • strumpellin and WASH-interacting protein
• GenBank acession
  • AB028956
• Locus
  12q23.3
• Discovery year
  2005-03-01
• Entrez gene record
  23325
• Pubmed identfication
  • 20376207
  • 20498093
  • 21498477
• RefSeq identity
  • NM_015275
• Classification
  • WASH complex
• VEGA ID
  OTTHUMG00000169838

Gene info

• Identity
  HGNC:28984
• Gene
  WASHC5
• Long gene name
  WASH complex subunit 5
• Synonyms gene
  • SPG8
  • KIAA0196
• Synonyms gene name
  • spastic paraplegia 8 (autosomal dominant)
  • KIAA0196
• Synonyms name
  • strumpellin
• Locus
  8q24.13
• Discovery year
  2005-07-19
• Entrez gene record
  9897
• Pubmed identfication
  • 9973294
  • 17160902
  • 23085491
• RefSeq identity
  • NM_014846
• Classification
  • WASH complex
• VEGA ID
  OTTHUMG00000164991

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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