anti-SPRYD2 Antibody

• Catalog number
  6403
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SPRYD2 Antibody: SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
• Gene names
  SPRYD2 Antibody: SPRYD2, TRIM76, C5orf10, DTNBP2, SPRYD2, Cardiomyopathy-associated protein 5, Dystrobrevin-binding protein 2
• Antibodie s label
  unlabelled serum
• Purity
  SPRYD2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
• Antigen
  SPRYD2 antibody was made against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  SPRYD2 antibody can be used for detection of SPRYD2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  SPRYD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SPRYD2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  62241003
• Ncbi nr
  NP_705838
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  202333
• GENE symbol
  CMYA5
• Antigene name
  cardiomyopathy associated 5
• Source
  Homo sapiens
• Protein nr
  Q8N3K9
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SPRYD2  
• Gene symbol
  CMYA5
• Short name
  anti-SPRYD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSPRYD2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14305
• Gene
  CMYA5
• Long gene name
  cardiomyopathy associated 5
• Synonyms gene
  • C5orf10
• Synonyms gene name
  • chromosome 5 open reading frame 10
• Synonyms
  • SPRYD2
  • DKFZp451G223
  • TRIM76
• Synonyms name
  • genethonin-3
  • tripartite motif-containing 76
  • myospryn
• GenBank acession
  • AW755254
  • AL831986
• Locus
  5q14.1
• Discovery year
  2002-03-25
• Entrez gene record
  202333
• Pubmed identfication
  • 14688250
  • 21427212
• RefSeq identity
  • NM_153610
• Classification
  • Fibronectin type III domain containing
  • Tripartite motif containing
  • A-kinase anchoring proteins
• VEGA ID
  OTTHUMG00000162548

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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