anti-SIRT3 Antibody

• Catalog number
  5767
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SIRT3 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.
• Gene names
  SIRT3 Antibody: SIR2L3, SIR2L3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Regulatory protein SIR2 homolog 3, hSIRT3
• Antibodie s label
  unlabelled serum
• Purity
  SIRT3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Chicken
• Type
  Polyclonal
• Immunoglobulin
  IgY
• Antigen
  SIRT3 antibody was made against a 17 amino acid synthetic peptide near the center of human SIRT3.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  SIRT3 antibody can be used for detection of SIRT3 by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  SIRT3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SIRT3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  6912660
• Ncbi nr
  NP_036371
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  23410
• GENE symbol
  SIRT3
• Antigene name
  sirtuin 3
• Source
  Homo sapiens
• Protein nr
  Q9NTG7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIRT3  
• Gene symbol
  SIRT3
• Short name
  anti-SIRT3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSIRT3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14931
• Gene
  SIRT3
• Long gene name
  sirtuin 3
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3
  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
• Synonyms
  • SIR2L3
• GenBank acession
  • AF083108
• Locus
  11p15.5
• Discovery year
  2001-03-20
• Entrez gene record
  23410
• Pubmed identfication
  • 10381378
  • 18215119
• Classification
  • Sirtuins
• VEGA ID
  OTTHUMG00000119074

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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