anti-RUVBL1 Antibody
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Catalog number25-060
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PricePlease ask
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Size50 ug
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Gene infoRUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex.
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Gene namesRUVBL1, ECP54, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49A, INO80H, PONTIN
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUVBL1.
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Immuno applicationELISA, Western Blot
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Antibody adviceRUVBL1 antibody can be used for detection of RUVBL1 by ELISA at 1:312500. RUVBL1 antibody can be used for detection of RUVBL1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store RUVBL1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman, Mouse, Rat
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Omim nr4506753
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Ncbi nrNP_003698
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KDa50 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr8607
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GENE symbolRUVBL1
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Antigene nameRuvB-like AAA ATPase 1
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SourceHomo sapiens
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Protein nrQ9Y265
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRUVBL1-AS1, RUVBL1
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Short nameanti-RUVBL1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toRUVBL1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRUVBL1 antisense RNA 1
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Synonyms gene name
- RUVBL1 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-07-28
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRuvB like AAA ATPase 1
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Synonyms gene name
- RuvB (E coli homolog)-like 1
- RuvB-like 1 (E. coli)
- RuvB-like AAA ATPase
- RuvB-like AAA ATPase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-19
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Entrez gene record
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Pubmed identfication
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Classification
- R2SP complex
- AAA ATPases
- R2TP complex
- INO80 complex
- SRCAP complex
- DNA helicases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
