anti-RGS22 Antibody

• Catalog number
  7001
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  RGS22 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.
• Gene names
  RGS22 Antibody: CT145, PRTD-NY2, Regulator of G-protein signaling 22, RGS22
• Antibodie s label
  unlabelled serum
• Purity
  RGS22 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  At least four isoforms of RGS22 are known to exist; this antibody will detect the three longest isoforms. RGS22 antibody is predicted to not cross-react with other RGS proteins
• Antigen
  RGS22 antibody was made against a 19 amino acid synthetic peptide near the amino terminus of human RGS22.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  RGS22 antibody can be used for detection of RGS22 by Western blot at 1 - 2 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  RGS22 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  RGS22 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  158534077
• Ncbi nr
  NP_056483
• KDa
  139 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  26166
• GENE symbol
  RGS22
• Antigene name
  regulator of G-protein signaling 22
• Source
  homo sapiens
• Protein nr
  Q8NE09
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RGS22  
• Gene symbol
  RGS22
• Short name
  anti-RGS22 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toRGS22 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24499
• Gene
  RGS22
• Long gene name
  regulator of G protein signaling 22
• Synonyms gene name
  • regulator of G-protein signalling 22
  • regulator of G-protein signaling 22
• Synonyms
  • DKFZP434I092
  • PRTD-NY2
  • CT145
• GenBank acession
  • AY009106
• Locus
  8q22.2
• Discovery year
  2005-02-23
• Entrez gene record
  26166
• RefSeq identity
  • NM_015668
• Classification
  • Regulators of G-protein signaling
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000164802

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products