anti-RAP80 Antibody

• Catalog number
  4325
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  RAP80 Antibody: RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR). Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1. At least four isoforms of RAP80 are known to exist.
• Gene names
  RAP80 Antibody: RAP80, X2HRIP110, RAP80, RXRIP110, BRCA1-A complex subunit RAP80, Receptor-associated protein 80
• Antibodie s label
  unlabelled serum
• Purity
  RAP80 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  RAP80 antibody was made against a 17 amino acid synthetic peptide from near the carboxy terminus of human RAP80.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  RAP80 antibody can be used for detection of RAP80 by Western blot at 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  RAP80 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  RAP80 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  119605449
• Ncbi nr
  EAW85043
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  51720
• GENE symbol
  UIMC1
• Antigene name
  ubiquitin interaction motif containing 1
• Source
  Homo sapiens
• Protein nr
  Q96RL1
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RAP80  
• Gene symbol
  UIMC1
• Short name
  anti-RAP80 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toRAP80 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30298
• Gene
  UIMC1
• Long gene name
  ubiquitin interaction motif containing 1
• Synonyms
  • RAP80
• Synonyms name
  • receptor associated protein 80
• GenBank acession
  • AF349313
• Locus
  5q35.2
• Discovery year
  2006-10-27
• Entrez gene record
  51720
• Pubmed identfication
  • 12080054
  • 19015238
• RefSeq identity
  • NM_016290
• Classification
  • BRCA1 A complex
• VEGA ID
  OTTHUMG00000130852

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products