anti-PTCHD2 Antibody

• Catalog number
  4915
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.
• Gene names
  PTCHD2 Antibody: DISP3, DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3
• Antibodie s label
  unlabelled serum
• Purity
  PTCHD2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  At least two isoforms of PTCHD2 are known to exist. This antibody is specific for PTCHD2 and will not recognize the other DISP family of proteins.
• Antigen
  PTCHD2 antibody was made against a 14 amino acid synthetic peptide from near the carboxy terminus of human PTCHD2.
• Immuno application
  ELISA, immuno-histo-chemistry
• Antibody advice
  PTCHD2 antibody can be used for detection of PTCHD2 by immunohistochemistry at 5 ug/mL.
• Suspention pH azide
  PTCHD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PTCHD2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  149274653
• Ncbi nr
  Q9P2K9
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  57540
• GENE symbol
  PTCHD2
• Antigene name
  patched domain containing 2
• Source
  Homo sapiens
• Protein nr
  Q9P2K9
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PTCHD2  
• Gene symbol
  DISP3
• Short name
  anti-PTCHD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPTCHD2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29251
• Gene
  DISP3
• Long gene name
  dispatched RND transporter family member 3
• Synonyms gene
  • PTCHD2
• Synonyms gene name
  • patched domain containing 2
• Synonyms
  • KIAA1337
• Synonyms name
  • dispatched homolog 3 (Drosophila)
• GenBank acession
  • AB037758
• Locus
  1p36.22
• Discovery year
  2005-05-24
• Entrez gene record
  57540
• Pubmed identfication
  • 15738394
  • 25281927
• RefSeq identity
  • NM_020780
• VEGA ID
  OTTHUMG00000002074

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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