anti-PRICKLE2 Antibody

• Catalog number
  6563
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
• Gene names
  PRICKLE2 Antibody: EPM5, Prickle-like protein 2
• Antibodie s label
  unlabelled serum
• Purity
  PRICKLE2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.
• Antigen
  PRICKLE2 antibody was made against a 15 amino acid synthetic peptide near the center of human PRICKLE2.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  PRICKLE2 antibody can be used for detection of PRICKLE2 by Western blot at 1 ug/mL. Antibody can also be used for immunofluorescence starting at 20 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  PRICKLE2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PRICKLE2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  38524620
• Ncbi nr
  NP_942559
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  166336
• GENE symbol
  PRICKLE2
• Antigene name
  prickle homolog 2
• Source
  Homo sapiens
• Protein nr
  Q7Z3G6
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PRICKLE2  
• Gene symbol
  PRICKLE2-DT, PRICKLE2-AS3, PRICKLE2-AS1, PRICKLE2, PRICKLE2-AS2
• Short name
  anti-PRICKLE2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPRICKLE2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:52829
• Gene
  PRICKLE2-DT
• Long gene name
  PRICKLE2 divergent transcript
• Locus
  3p14.1
• Discovery year
  2019-05-17
• Entrez gene record
  101929316
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:40918
• Gene
  PRICKLE2-AS3
• Long gene name
  PRICKLE2 antisense RNA 3
• Synonyms gene name
  • PRICKLE2 antisense RNA 3 (non-protein coding)
• Locus
  3p14.1
• Discovery year
  2011-07-28
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000158795

Gene info

• Identity
  HGNC:40916
• Gene
  PRICKLE2-AS1
• Long gene name
  PRICKLE2 antisense RNA 1
• Synonyms gene name
  • PRICKLE2 antisense RNA 1 (non-protein coding)
• Locus
  3p14.1
• Discovery year
  2011-07-28
• Entrez gene record
  100652759
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000158793

Gene info

• Identity
  HGNC:20340
• Gene
  PRICKLE2
• Long gene name
  prickle planar cell polarity protein 2
• Synonyms gene name
  • prickle-like 2 (Drosophila)
  • prickle homolog 2 (Drosophila)
• Synonyms
  • DKFZp686D143
• GenBank acession
  • AK127839
• Locus
  3p14.1
• Discovery year
  2003-02-10
• Entrez gene record
  166336
• Pubmed identfication
  • 12525887
• RefSeq identity
  • NM_198859
• Classification
  • LIM domain containing
  • Prickle planar cell polarity proteins
• VEGA ID
  OTTHUMG00000158789

Gene info

• Identity
  HGNC:40917
• Gene
  PRICKLE2-AS2
• Long gene name
  PRICKLE2 antisense RNA 2
• Synonyms gene name
  • PRICKLE2 antisense RNA 2 (non-protein coding)
• Locus
  3p14.1
• Discovery year
  2011-07-28
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000158792

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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