anti-Precerebellin Antibody
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Catalog number
3587
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.
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Gene names
Precerebellin Antibody: Cerebellin-1, Precerebellin, CER
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Antibodie s label
unlabelled serum
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Purity
Precerebellin Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
Precerebellin antibody was made against a 16 amino acid synthetic peptide from near the carboxy- terminus human precerebellin.
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Immuno application
ELISA, Western Blot, immuno-cyto-chemistry
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Antibody advice
Precerebellin antibody can be used for the detection of precerebellin by Western blot at 2 - 4 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL.
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Suspention pH azide
Precerebellin Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Precerebellin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
116114
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Ncbi nr
P23435
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
869
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GENE symbol
CBLN1
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Antigene name
cerebellin 1 precursor
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Source
Homo sapiens
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Protein nr
P23435
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-Precerebellin Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toPrecerebellin (antibody to-)
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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