anti-Potassium Channel (phospho Ser503) Antibody
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Catalog number
50-235
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Price
Please ask
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Size
0.1 mL
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Gene info
Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).
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Gene names
Kv4, Kv3.1, KShIIIB, NGK2-KV4, NGK2,
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Antibodie s label
unlabelled serum
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Purity
Affinity Purified
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Ab raised in
Rabbit
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Type
Polyclonal
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Antigen
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH).
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Immuno application
Western Blot, immuno-histo-chemistry
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Antibody advice
The antibody has been directly tested for reactivity in Western blots with rat and mouse tissue.
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Suspention pH azide
100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
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Keep at
Potassium Channel antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
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Works with
Mouse, Rat
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Omim nr
116439
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Ncbi nr
P25122
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KDa
100
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Vial with antibody
in solution
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NCBI GENE nr
25327
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GENE symbol
Kcnc1
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Antigene name
potassium voltage gated channel, Shaw-related subfamily, member 1
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Source
Rattus norvegicus
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Protein nr
P25122
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-Potassium Channel (phospho Ser503) Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toPotassium Channel (phosphorilated Ser503) (antibody to-)
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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