anti-PMP22 Antibody

• Catalog number
  48-619
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  PMP22 is a major component of myelin expressed in the compact portion of essentially all myelinated fibers in the peripheral nervous system and is produced predominantly by Schwann cells. Studies in injured nerve suggested a role during Schwann cell growth and differentiation. PMP22 is expressed in cranial nerves but not in the mature central nervous system. Studies suggest a possible role of the PMP22 gene in the development of neoplasia in patients with neurofibromatosis and in the myelin degenerative Charcot-Marie-Tooth disease linked to chromosome 17p.
• Gene names
  PMP22, CMT1E, DSS, GAS-3, GAS3, Growth arrest-specific 3, HMSNIA, PMP-22, CMT1A, HNPP, Peripheral myelin protein 22
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  PMP22 antibody was made against a peptide near the C-Terminus of PMP22 (Human).
• Immuno application
  immuno-histo-chemistry
• Antibody advice
  PMP22 antibody can be used in ELISA, and immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
• Keep at
  Store PMP22 antibody at 4 grades C, Avoid Freezing
• Works with
  Human
• Omim nr
  266803
• Ncbi nr
  Q01453
• Vial with antibody
  in solution
• NCBI GENE nr
  5376
• GENE symbol
  PMP22
• Antigene name
  peripheral myelin protein 22
• Source
  Homo sapiens
• Protein nr
  Q01453
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PMP22  
• Gene symbol
  PXMP2, PMP22
• Short name
  anti-PMP22 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPMP22 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9716
• Gene
  PXMP2
• Long gene name
  peroxisomal membrane protein 2
• Synonyms gene name
  • peroxisomal membrane protein 2 (22kD)
  • peroxisomal membrane protein 2, 22kDa
• Synonyms
  • PMP22
  • MPV17L3
• Locus
  12q24.33
• Discovery year
  1992-03-03
• Entrez gene record
  5827
• Pubmed identfication
  • 11590176
  • 19352492
• RefSeq identity
  • NM_018663
• VEGA ID
  OTTHUMG00000168019

Gene info

• Identity
  HGNC:9118
• Gene
  PMP22
• Long gene name
  peripheral myelin protein 22
• Synonyms gene
  • CMT1A
• Synonyms gene name
  • Charcot-Marie-Tooth neuropathy 1A (greatly reduced nerve conduction velocity, hereditary motor sensory neuropathy Ia)
• Synonyms
  • HNPP
  • GAS3
  • Sp110
  • HMSNIA
• GenBank acession
  • D11428
• Locus
  17p12
• Discovery year
  1992-11-05
• Entrez gene record
  5376
• Pubmed identfication
  • 8482547
  • 1497668
  • 8252046
• RefSeq identity
  • NM_000304
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000058960
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_263

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products