anti-PLK1 (phospho Thr210 ) Antibody

• Catalog number
  50-249
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK’s is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).
• Gene names
  PLK, STPK13, PLK, Polo-like kinase 1, PLK-1
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr210 of PLK1.
• Immuno application
  Western Blot
• Antibody advice
  The antibody has been directly tested for reactivity in Western blots in rat and human tissues. It is anticipated that the antibody will react with bovine, canine, mouse, non-human primate, Xenopus and Zebrafish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  PLK1 antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Dog, Zebrafish, Bovine, Xenopus
• Omim nr
  1709658
• Ncbi nr
  P53350
• KDa
  66
• Vial with antibody
  in solution
• NCBI GENE nr
  5347
• GENE symbol
  PLK1
• Antigene name
  polo-like kinase 1
• Source
  Homo sapiens
• Protein nr
  P53350
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PLK1   phospho   Thr210  
• Gene symbol
  PLK1
• Short name
  anti-PLK1 (phospho Thr210 ) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPLK1 (phosphorilated Thr210 ) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9077
• Gene
  PLK1
• Long gene name
  polo like kinase 1
• Synonyms gene
  • PLK
• Synonyms gene name
  • polo-like kinase (Drosophila)
  • polo-like kinase 1
• Locus
  16p12.2
• Discovery year
  1994-07-25
• Entrez gene record
  5347
• Pubmed identfication
  • 8127874
• RefSeq identity
  • NM_005030
• VEGA ID
  OTTHUMG00000096984

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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