anti-PDE Antibody
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Catalog number31-306
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PricePlease ask
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Size50 ug
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Gene info2'-PDE is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2'-PDE also cleaves 3',5'-phosphodiester bond of oligoadenylates. 2'-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
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Gene names2'-PDE, 2'-PDE
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDE.
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Immuno applicationELISA, Western Blot
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Antibody advicePDE antibody can be used for detection of PDE by ELISA at 1:1562500. PDE antibody can be used for detection of PDE by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store PDE antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman, Mouse
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Omim nr189027129
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Ncbi nrNP_808881
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KDa67 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr201626
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GENE symbolPDE12
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Antigene namephosphodiesterase 12
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SourceHomo sapiens
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Protein nrQ6L8Q7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPDE3A, ALDH7A1, PDE12
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Short nameanti-PDE Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toPDE (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namephosphodiesterase 3A
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Synonyms gene name
- phosphodiesterase 3A, cGMP-inhibited
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-07-29
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Entrez gene record
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Pubmed identfication
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Classification
- Phosphodiesterases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namealdehyde dehydrogenase 7 family member A1
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Synonyms gene
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Synonyms gene name
- aldehyde dehydrogenase 7 family, member A1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aldehyde dehydrogenases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namephosphodiesterase 12
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2008-02-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
