anti-PAK6 Antibody
-
Catalog number3073
-
PricePlease ask
-
Size0.02 mg, 0.1 mg
-
-
Gene infoPAK6 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.
-
Gene namesPAK6 Antibody: PAK5, PAK5, PAK-5, PAK-6
-
Antibodie s labelunlabelled serum
-
PurityPAK6 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
AntigenPAK6 antibody was made against a 13 amino acid synthetic peptide from near the center of human PAK6.
-
Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
-
Antibody advicePAK6 antibody can be used for the detection of PAK6 by Western blot at 1 - 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 10 ug/mL.
-
Suspention pH azidePAK6 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atPAK6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works withHuman
-
Omim nr9910476
-
Ncbi nrNP_064553
-
Vial with antibodyin solution
-
Quantity per ml1 mg/mL
-
NCBI GENE nr56924
-
GENE symbolPAK6
-
Antigene namep21 protein (Cdc42/Rac)-activated kinase 6
-
SourceHomo sapiens
-
Protein nrQ9NQU5
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolBUB1B-PAK6, PAK6, PAK6-AS1
-
Short nameanti-PAK6 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toPAK6 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameBUB1B-PAK6 readthrough
-
Locus
-
Discovery year2017-01-23
-
Entrez gene record
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namep21 (RAC1) activated kinase 6
-
Synonyms gene name
- p21(CDKN1A)-activated kinase 6
- p21 protein (Cdc42/Rac)-activated kinase 6
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-07-12
-
Entrez gene record
-
Pubmed identfication
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namePAK6 antisense RNA 1
-
Synonyms gene
-
Synonyms gene name
- chromosome 15 open reading frame 56
- chromosome 15 putative open reading frame 56
-
Synonyms
-
Locus
-
Discovery year2007-12-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data