anti-PAK5 Antibody

• Catalog number
  3075
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PAK5 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.
• Gene names
  PAK5 Antibody: PAK5, KIAA1264, PAK5, p21-activated kinase 5, PAK-5
• Antibodie s label
  unlabelled serum
• Purity
  PAK5 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PAK5 antibody was made against a 13 amino acid synthetic peptide from near the center of human PAK5.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
• Antibody advice
  PAK5 antibody can be used for the detection of PAK5 by Western blot at 2 - 4 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 10 ug/mL.
• Suspention pH azide
  PAK5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PAK5 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  12585290
• Ncbi nr
  Q9P286
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  57144
• GENE symbol
  PAK7
• Antigene name
  p21 protein (Cdc42/Rac)-activated kinase 7
• Source
  Homo sapiens
• Protein nr
  Q9P286
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PAK5  
• Gene symbol
  PAK6, PAK5
• Short name
  anti-PAK5 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPAK5 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16061
• Gene
  PAK6
• Long gene name
  p21 (RAC1) activated kinase 6
• Synonyms gene name
  • p21(CDKN1A)-activated kinase 6
  • p21 protein (Cdc42/Rac)-activated kinase 6
• Synonyms
  • PAK5
• GenBank acession
  • AF276893
• Locus
  15q15.1
• Discovery year
  2001-07-12
• Entrez gene record
  56924
• Pubmed identfication
  • 11278661
• VEGA ID
  OTTHUMG00000129921

Gene info

• Identity
  HGNC:15916
• Gene
  PAK5
• Long gene name
  p21 (RAC1) activated kinase 5
• Synonyms gene
  • PAK7
• Synonyms gene name
  • p21(CDKN1A)-activated kinase 7
  • p21 protein (Cdc42/Rac)-activated kinase 7
  • p21 (RAC1) activated kinase 7
• Synonyms
  • KIAA1264
• GenBank acession
  • AB033090
• Locus
  20p12.2
• Discovery year
  2001-06-21
• Entrez gene record
  57144
• Pubmed identfication
  • 11756552
  • 10574462
• VEGA ID
  OTTHUMG00000031857

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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