anti-ORAI1 Antibody [3F6H5]
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Catalog number
PM-5205
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
ORAI1 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one fo rm of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
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Gene names
ORAI1 Antibody [3F6H5] : IMD9, ORAT1, CRACM1, TMEM142A
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Antibodie s label
unlabelled serum
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Purity
ORAI1 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
3F6H5
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Immunoglobulin
IgG1
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Spicific to
ORAI1 antibody is predicted to have no cross reactivity to other members in the ORAI family.
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Antigen
Mouse monoclonal ORAI1 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
ORAI1 antibody can be used for detection of ORAI1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
ORAI1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
ORAI1 monoclonal antibody can be stored at -20 grades C, stable for one year.
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Works with
Human, Mouse, Rat
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Omim nr
97180269
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Ncbi nr
Q96D31
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KDa
Predicted: 33 kDa Observed: 56 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
84876
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GENE symbol
ORAI1
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Antigene name
ORAI calcium release-activated calcium modulator 1
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Source
homo sapiens
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Protein nr
Q96D31
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ORAI1
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Short name
anti-ORAI1 Antibody [3F6H5]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toORAI1 (antibody to-) [3F6H5]
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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