anti-NFIL3 Antibody
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Catalog number28-908
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PricePlease ask
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Size100 ug
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Gene infoNFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
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Gene namesNFIL3, E4BP4, IL3BP1, NFIL3A, NF-IL3A
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by protein A chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.
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Immuno applicationELISA, Western Blot
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Antibody adviceNFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store NFIL3 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr52630429
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Ncbi nrNP_005375
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KDa51 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr4783
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GENE symbolNFIL3
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Antigene namenuclear factor, interleukin 3 regulated
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SourceHomo sapiens
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Protein nrQ14211
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNFIL3
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Short nameanti-NFIL3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toNFIL3 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetnuclear factor, interleukin 3 regulated, E4BP4 and IL3BP1 and NF-IL3A and NFIL3A, NFIL3 and IDBG-75722 and ENSG00000165030 and 4783, sequence-specific DNA binding, nuclei, Nfil3 and IDBG-152923 and ENSMUSG00000056749 and 18030, NFIL3 and IDBG-647479 and ENSBTAG00000017763 and 506097
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Gene info
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Identity
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Gene
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Long gene namenuclear factor, interleukin 3 regulated
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Synonyms gene
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Synonyms gene name
- interleukin-3 binding protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-02-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic leucine zipper proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data