anti-Neurotrypsin Antibody

• Catalog number
  4105
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Neurotrypsin Antibody: Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
• Gene names
  Neurotrypsin Antibody: MRT1, BSSP3, BSSP-3, Neurotrypsin, Leydin
• Antibodie s label
  unlabelled serum
• Purity
  Neurotrypsin Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Neurotrypsin antibody was made against a 23 amino acid synthetic peptide from near the amino terminus of human neurotrypsin.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Neurotrypsin antibody can be used for detection of neurotrypsin by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  Neurotrypsin Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Neurotrypsin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  2661424
• Ncbi nr
  CAA04816
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  8492
• GENE symbol
  PRSS12
• Antigene name
  protease, serine, 12 (neurotrypsin, motopsin)
• Source
  Homo sapiens
• Protein nr
  P56730
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Neurotrypsin  
• Gene symbol
  PRSS12
• Short name
  anti-Neurotrypsin Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNeurotrypsin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9477
• Gene
  PRSS12
• Long gene name
  serine protease 12
• Synonyms gene name
  • protease, serine 12
• Synonyms
  • BSSP-3
  • MRT1
• Synonyms name
  • neurotrypsin
  • motopsin
  • brain-specific serine protease 3
  • mental retardation, autosomal recessive 1
• GenBank acession
  • AJ001531
• Locus
  4q26
• Discovery year
  1998-10-02
• Entrez gene record
  8492
• Pubmed identfication
  • 9540828
  • 9245503
• Classification
  • Scavenger receptor cysteine rich domain containing
  • Serine proteases
• VEGA ID
  OTTHUMG00000161166

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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