anti-Neurofibromin 2 (phospho Ser518) Antibody

• Catalog number
  49-453
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  The recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin). The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlin's similarity to ERMs suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane. The NF2 protein is highly expressed in human fibroblasts and is detected as a single band of about 75 kDa. This antibody is specific for the phosphorylated form of human NF2 (Merlin).
• Gene names
  NF2, ACN, BANF, Moesin-ezrin-radixin like, Neurofibromin 2 (merlin), Neurofibromin-2, SCH, Merlin, Schwannomerlin, Schwannomin
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  pSer518
• Antigen
  Human NF2 (Merlin) phospho-peptide corresponding to a region of the human protein surrounding S518 and conjugated to Keyhole Limpet Hemocyanin (KLH).
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno precipitation
• Antibody advice
  Neurofibromin 2 antibody can be used in ELISA, and immunohistochemistry starting at 2.5 ug/mL.
• Suspention pH azide
  0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
• Keep at
  Store Neurofibromin 2 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse
• Omim nr
  462594
• Ncbi nr
  P35240
• Vial with antibody
  in solution
• NCBI GENE nr
  4771
• GENE symbol
  NF2
• Antigene name
  neurofibromin 2 (merlin)
• Source
  Homo sapiens
• Protein nr
  P35240
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Neurofibromin   phospho   Ser518  
• Short name
  anti-Neurofibromin 2 (phospho Ser518) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNeurofibromin 2 (phosphorilated Ser518) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products