anti-NEUCRIN Antibody
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Catalog number6493
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoNEUCRIN Antibody: Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.
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Gene namesNEUCRIN Antibody: UNQ3119, neucrin, AGPA3119, C1orf187, PSEC0258, UNQ3119/PRO10268, Draxin, Dorsal inhibitory axon guidance protein
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Antibodie s labelunlabelled serum
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PurityNEUCRIN Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toAt least three isoforms of Neucrin are known to exist; this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.
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AntigenNeucrin antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of human Neucrin.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceNeucrin antibody can be used for detection of Neucrin by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideNEUCRIN Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atNEUCRIN antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr86990448
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Ncbi nrBAG80561
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr374946
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GENE symbolC1orf187
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Antigene namechromosome 1 open reading frame 187
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SourceHomo sapiens
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Protein nrQ8NBI3
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDRAXIN
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Short nameanti-NEUCRIN Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toNEUCRIN (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namedorsal inhibitory axon guidance protein
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Synonyms gene
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Synonyms gene name
- chromosome 1 open reading frame 187
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-08-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data