anti-MEK5 (phospho Ser311 / Thr315) Antibody

• Catalog number
  50-245
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004).
• Gene names
  Mek5, Mek5, Mkk5, Prkmk5, MAP kinase kinase 5
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5.
• Immuno application
  Western Blot
• Antibody advice
  The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse, human, chicken, bovine, canine, non-human primate, Xenopus, and Zebrafish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  MEK5 antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Dog, Zebrafish, Bovine, Chcicken, Xenopus
• Omim nr
  2499634
• Ncbi nr
  Q62862
• KDa
  49
• Vial with antibody
  in solution
• NCBI GENE nr
  29568
• GENE symbol
  Map2k5
• Antigene name
  mitogen activated protein kinase kinase 5
• Source
  Rattus norvegicus
• Protein nr
  Q62862
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEK5   phospho   Ser311   Thr315  
• Gene symbol
  MAP2K5
• Short name
  anti-MEK5 (phospho Ser311 / Thr315) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMEK5 (phosphorilated Ser311 / Thr315) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6845
• Gene
  MAP2K5
• Long gene name
  mitogen-activated protein kinase kinase 5
• Synonyms gene
  • PRKMK5
• Synonyms
  • MEK5
  • MAPKK5
  • HsT17454
• GenBank acession
  • U25265
• Locus
  15q23
• Discovery year
  1997-11-11
• Entrez gene record
  5607
• Pubmed identfication
  • 7759517
• RefSeq identity
  • NM_145162
• Classification
  • Mitogen-activated protein kinase kinases
• VEGA ID
  OTTHUMG00000133264

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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