anti-LASS5 Antibody
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Catalog number4697
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoLASS5 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis.
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Gene namesLASS5 Antibody: Trh4, LASS5, Ceramide synthase 5, LAG1 longevity assurance homolog 5, CerS5
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Antibodie s labelunlabelled serum
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PurityLASS5 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toMultiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.
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AntigenLASS5 antibody was made against a 18 amino acid synthetic peptide near the amino terminus of the human LASS5.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceLASS5 antibody can be used for detection of LASS5 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideLASS5 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atLASS5 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr22218345
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Ncbi nrNP_671723
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr91012
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GENE symbolLASS5
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Antigene nameLAG1 homolog, ceramide synthase 5
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SourceHomo sapiens
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Protein nrQ8N5B7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCERS5
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Short nameanti-LASS5 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toLASS5 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameceramide synthase 5
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Synonyms gene
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Synonyms gene name
- LAG1 longevity assurance homolog 5 (S. cerevisiae)
- LAG1 homolog, ceramide synthase 5
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Synonyms
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Locus
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Discovery year2003-12-11
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Entrez gene record
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RefSeq identity
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Classification
- CERS class homeoboxes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
