anti-KPNA1 Antibody
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Catalog number5981
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoKPNA1 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.
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Gene namesKPNA1 Antibody: RCH2, SRP1, IPOA5, NPI-1, RCH2, Importin subunit alpha-5, Karyopherin subunit alpha-1
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Antibodie s labelunlabelled serum
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PurityKPNA1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenKPNA1 antibody was made against a 15 amino acid synthetic peptide near the amino terminus of human KPNA1.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
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Antibody adviceKPNA1 antibody can be used for detection of KPNA1 by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideKPNA1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atKPNA1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr222144293
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Ncbi nrNP_002255
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr3836
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GENE symbolKPNA1
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Antigene namekaryopherin alpha 1 (importin alpha 5)
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SourceHomo sapiens
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Protein nrP52294
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolKPNA1
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Short nameanti-KPNA1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toKPNA1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namekaryopherin subunit alpha 1
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Synonyms gene name
- karyopherin alpha 1 (importin alpha 5)
- karyopherin alpha 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Importins
- Armadillo repeat containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data