anti-IL-13 Antibody

• Catalog number
  XP-5168Bt
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  L13 inhibits proinflammatory cytokine production and stimulates antibody production. It induces proliferation in the human pre myeloid cell line TF1. IL13 has multiple effects on the differentiation and functions of monocytes and macrophages. It suppresses cytotoxic functions and induces changes in the morphology of human monocytes and in the phenotype of human monocytes and B cells by upregulating MHC class II expression. IL13 will also decrease the production of nitric oxide by activated murine macrophages, leading to impaired parasiticidal activity. Human and mouse interleukin 13 share approximately 58% amino acid sequence identity. Although human and mouse IL13 are equally active on human cells, human IL13 is much less active than mouse IL13 on mouse cells. Human IL13 and human IL4 also share approximately 30% sequence homology and have similar biological functions.
• Gene names
  Il-13, Il-13, Interleukin-13, T-cell activation protein P600, IL-13
• Antibodie s label
  Biotin
• Purity
  Anti-mIL-13 specific antibody was purified by affinity chromatography and then biotinylated.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-13 (murine IL-13).
• Immuno application
  ELISA, Western Blot
• Antibody advice
  ELISA:To detect mIL-13 by direct ELISA (using 100 μL/well antibody solution) this antibody can be used at a concentration of 0.15 - 0.30 ug/mL. Used in conjunction with compatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinant mIL-13. Sandwich:To detect mIL-13 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25 - 1.0 ug/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with our Polyclonal Anti-Murine IL-13 (XP-5168) as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-13.Western Blot:To detect mIL-13 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-13 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
• Keep at
  IL-13 antibody is stable for at least 2 years from date of receipt at -20 grades C. The reconstituted antibody is stable for at least two weeks at 2-8 grades C. Frozen aliquots are stable for at least 6 months when stored at -20 grades C. Avoid repeated freeze-thaw cycles.
• Works with
  Mouse
• Omim nr
  129377
• Ncbi nr
  P20109
• Vial with antibody
  Lyophilized
• NCBI GENE nr
  16163
• GENE symbol
  Il13
• Antigene name
  interleukin 13
• Source
  Mus musculus
• Protein nr
  P20109
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IL-13  
• Gene symbol
  IL13, PIRC58, SNORD115-13, SNORD114-13, IGHV3OR16-13, IGLV3-13, ERVK-13, SNORD116-13, IL36G, IL25
• Short name
  anti-IL-13 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIL-13 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5973
• Gene
  IL13
• Long gene name
  interleukin 13
• Synonyms
  • P600
  • IL-13
  • ALRH
  • BHR1
  • MGC116786
  • MGC116788
  • MGC116789
• Synonyms name
  • allergic rhinitis
  • Bronchial hyperresponsiveness-1 (bronchial asthma)
• GenBank acession
  • U31120
• Locus
  5q31.1
• Discovery year
  1993-04-07
• Entrez gene record
  3596
• RefSeq identity
  • NM_002188
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000059723

Gene info

• Identity
  HGNC:37562
• Gene
  PIRC58
• Long gene name
  piwi-interacting RNA cluster 58
• Locus
  13
• Discovery year
  2009-11-05
• Entrez gene record
  100313918
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33032
• Gene
  SNORD115-13
• Long gene name
  small nucleolar RNA, C/D box 115-13
• Synonyms
  • HBII-52-13
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033450
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003305.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33001
• Gene
  SNORD114-13
• Long gene name
  small nucleolar RNA, C/D box 114-13
• Synonyms
  • 14q(II-13)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767591
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003206.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5637
• Gene
  IGHV3OR16-13
• Long gene name
  immunoglobulin heavy variable 3/OR16-13 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-13
• Synonyms
  • IGHV3/OR16-13
• GenBank acession
  • Z29610
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100287372
• RefSeq identity
  • NG_011771
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176357

Gene info

• Identity
  HGNC:5899
• Gene
  IGLV3-13
• Long gene name
  immunoglobulin lambda variable 3-13 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable 3-13
  • immunoglobulin lambda variable 3-13 pseudogene
• GenBank acession
  • X97463
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28801
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151215

Gene info

• Identity
  HGNC:39008
• Gene
  ERVK-13
• Long gene name
  endogenous retrovirus group K member 13
• Synonyms gene name
  • endogenous retrovirus group K, member 13
• Synonyms
  • c3_D
• GenBank acession
  • FN806832
• Locus
  3q24
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18664271
  • 21542922

Gene info

• Identity
  HGNC:33079
• Gene
  SNORD116-13
• Long gene name
  small nucleolar RNA, C/D box 116-13
• Synonyms
  • HBII-85-13
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033425
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003328
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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