anti-IKBKG Antibody

• Catalog number
  27-263
• Price
  Please ask
• Size
  100 ug

• Gene info
  Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males . In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito
• Gene names
  IKBKG, IP, IP1, IP2, FIP3, IPD2, NEMO, FIP-3, Fip3p, AMCBX1, ZC2HC9, IKK-gamma
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IKBKG.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  IKBKG antibody can be used for detection of IKBKG by ELISA at 1:312500. IKBKG antibody can be used for detection of IKBKG by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store IKBKG antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Dog
• Omim nr
  4504631
• Ncbi nr
  NP_003630
• KDa
  48 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  8517
• GENE symbol
  IKBKG
• Antigene name
  inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
• Source
  Homo sapiens
• Protein nr
  Q9Y6K9
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IKBKG  
• Gene symbol
  IKBKG
• Short name
  anti-IKBKG Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIKBKG (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, AMCBX1 and FIP-3 and FIP3 and Fip3p and IKK-gamma and IMD33 and IP and IP1 and IP2 and IPD2 and NEMO and ZC2HC9, IKBKG and IDBG-777831 and ENSG00000269335 and 8517, protein heterodimerization activity, nuclei, Ikbkg and IDBG-156458 and ENSMUSG00000004221 and 16151, IKBKG and IDBG-633075 and ENSBTAG00000006268 and 281855

Gene info

• Identity
  HGNC:5961
• Gene
  IKBKG
• Long gene name
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
• Synonyms gene
  • IP2
  • IP1
• Synonyms gene name
  • incontinentia pigmenti
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • inhibitor of nuclear factor kappa B kinase subunit gamma
• Synonyms
  • IKK-gamma
  • NEMO
  • Fip3p
  • FIP-3
  • FIP3
  • ZC2HC9
  • IKKAP1
  • IKKG
• Synonyms name
  • NF-kappa-B essential modulator
  • IkB kinase-associated protein 1
  • I-kappa-B kinase subunit gamma
  • IkB kinase subunit gamma
  • 14.7K (adenovirus E3 protein) interacting protein 3
• GenBank acession
  • AF074382
• Locus
  Xq28
• Discovery year
  1998-09-30
• Entrez gene record
  8517
• Pubmed identfication
  • 9751060
  • 10087442
  • 11590134
  • 11242109
• RefSeq identity
  • NM_003639
• Classification
  • Zinc fingers C2HC-type
  • IKK complex
• VEGA ID
  OTTHUMG00000024234
• Locus Specific Databases
  • IKBKGbase: Mutation registry for Nemo deficiency
  • Global Variome shared LOVD
  • LRG_70

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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