anti-IkB a (phospho Ser32 / Ser36) Antibody

• Catalog number
  79-175
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Inhibits the activity of dimeric NF-k-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.
• Gene names
  IKBA, MAD-3, NFKBI, ADDA, I-kappa-B-alpha, IKBA, NF-kappaB inhibitor alpha, NFKBIA
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of IkappaB-a; only when phosphorylated at serine 32/36.
• Antigen
  IkB-a (Phospho-Ser32/Ser36) antibody was made against a peptide sequence around phosphorylation site of serine 32/36 (H-D-S (p) -G-L-D-S (p) -M-K) derived from Human IkappaB-a;.
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  10092619
• Ncbi nr
  NP_065390.1
• KDa
  39 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  4792
• GENE symbol
  NFKBIA
• Antigene name
  nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
• Source
  Homo sapiens
• Protein nr
  P25963
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IkB   phospho   Ser32   Ser36  
• Short name
  anti-IkB a (phospho Ser32 / Ser36) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIkB a (phosphorilated Ser32 / Ser36) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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