anti-IDH1 Antibody
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Catalog number5819
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoIDH1 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. The presence of IDH1 in peroxisomes suggests it may play a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic IDH1 serves a significant role in cytoplasmic NADPH production. Defects in IDH1 are involved in the development of glioma.
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Gene namesIDH1 Antibody: IDH, IDP, IDCD, IDPC, PICD, HEL-216, HEL-S-26, Cytosolic NADP-isocitrate dehydrogenase, IDH
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Antibodie s labelunlabelled serum
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PurityIDH1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenIDH1 antibody was made against a 13 amino acid synthetic peptide near the carboxy terminus of human IDH1.
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Immuno applicationELISA, Western Blot
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Antibody adviceIDH1 antibody can be used for detection of IDH1 by Western blot at 1 - 2 ug/mL.
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Suspention pH azideIDH1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atIDH1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr28178825
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Ncbi nrNP_005887
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr3417
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GENE symbolIDH1
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Antigene nameisocitrate dehydrogenase 1 (NADP+), soluble
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SourceHomo sapiens
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Protein nrO75874
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIDH1, IDH1-AS1
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Short nameanti-IDH1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toIDH1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameisocitrate dehydrogenase (NADP(+)) 1
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Synonyms gene name
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase 1 (NADP+)
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Isocitrate dehydrogenases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameIDH1 antisense RNA 1
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Synonyms gene name
- IDH1 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2012-02-24
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Entrez gene record
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
