anti-HSD11B2 Antibody

• Catalog number
  XW-8141
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  FUNCTION: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.DISEASE: Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
• Gene names
  HSD11K, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, AME, AME1, HSD2, HSD11K, SDR9C3, Corticosteroid 11bdehydrogenase, isozyme 2, 11-beta-HSD2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Purified
• Ab raised in
  Chicken
• Type
  Polyclonal
• Antigen
  181-405
• Immuno application
  Western Blot
• Antibody advice
  Corticosteroid 11-β-dehydrogenase, isozyme 2 antibody can be used for the detection of Corticosteroid 11-β-dehydrogenase, isozyme 2 by Western Blot.
• Suspention pH azide
  Phosphate-Buffered Saline. No preservatives added.
• Keep at
  HSD11B2 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Rat, Chicken
• Omim nr
  4504499
• Ncbi nr
  NP_000187.1
• KDa
  44.1 kDa (calculated)
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  3291
• GENE symbol
  HSD11B2
• Antigene name
  hydroxysteroid (11-beta) dehydrogenase 2
• Source
  Homo sapiens
• Protein nr
  P80365
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HSD11B2  
• Gene symbol
  HSD11B2
• Short name
  anti-HSD11B2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toHSD11B2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5209
• Gene
  HSD11B2
• Long gene name
  hydroxysteroid 11-beta dehydrogenase 2
• Synonyms gene name
  • hydroxysteroid (11-beta) dehydrogenase 2
• Synonyms
  • SDR9C3
• Synonyms name
  • short chain dehydrogenase/reductase family 9C, member 3
• GenBank acession
  • U14631
• Locus
  16q22.1
• Discovery year
  1994-11-18
• Entrez gene record
  3291
• Pubmed identfication
  • 7859916
  • 8611140
  • 19027726
• RefSeq identity
  • NM_000196
• Classification
  • Short chain dehydrogenase/reductase superfamily
• VEGA ID
  OTTHUMG00000137507

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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