anti-HAVCR1 Antibody

• Catalog number
  49-280
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.
• Gene names
  HAVCR1, HAVCR-1, KIM-1, Kidney injury molecule 1, KIM1, T-cell membrane protein 1, TIM1, TIMD1, TIM-1, HAVCR, TIMD-1
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  HAVCR1 antibody was made against amino acids 200 - 300 of HAVCR1 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  HAVCR1 antibody can be used in immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  PBS, 0.05% BSA, 0.05% sodium azide.
• Keep at
  Store HAVCR1 antibody at 4 grades C for short term applications. For long term storage, aliquot and -20 grades C.
• Works with
  Human, Mouse
• Omim nr
  73919877
• Ncbi nr
  Q96D42
• Vial with antibody
  in solution
• NCBI GENE nr
  26762
• GENE symbol
  HAVCR1
• Antigene name
  hepatitis A virus cellular receptor 1
• Source
  Homo sapiens
• Protein nr
  Q96D42
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HAVCR1  
• Gene symbol
  HAVCR1
• Short name
  anti-HAVCR1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody tohepatitis A virus cellular receptor 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  hepatitis A virus cellular receptor 1, HAVCR1 and IDBG-55259 and ENSG00000113249 and 26762, protein binding, Plasma membranes

Gene info

• Identity
  HGNC:17866
• Gene
  HAVCR1
• Long gene name
  hepatitis A virus cellular receptor 1
• Synonyms
  • HAVCR-1
  • TIM-1
  • TIM1
  • HAVCR
  • TIMD1
  • CD365
  • KIM1
• Synonyms name
  • T-cell immunoglobulin mucin family member 1
  • kidney injury molecule 1
• GenBank acession
  • AF043724
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  26762
• Pubmed identfication
  • 9658108
  • 11725301
  • 18273441
• RefSeq identity
  • NM_012206
• Classification
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000163466

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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