anti-Grik4 Antibody

• Catalog number
  4393
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Grik4 Antibody: Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder.
• Gene names
  Grik4 Antibody: KA1, EAA1, GRIK, GluK4, Glutamate receptor ionotropic, kainate 4, Excitatory amino acid receptor 1
• Antibodie s label
  unlabelled serum
• Purity
  Grik4 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Grik4 antibody was made against a 14 amino acid synthetic peptide near the amino terminus of the human Grik4.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Grik4 antibody can be used for detection of Grik4 by Western blot at 0.5 - 2 ug/mL. Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  Grik4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Grik4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  209572625
• Ncbi nr
  Q16099
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  2900
• GENE symbol
  GRIK4
• Antigene name
  glutamate receptor, ionotropic, kainate 4
• Source
  Homo sapiens
• Protein nr
  Q16099
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Grik4  
• Gene symbol
  GRIK4
• Short name
  anti-Grik4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGrik4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4582
• Gene
  GRIK4
• Long gene name
  glutamate ionotropic receptor kainate type subunit 4
• Synonyms gene
  • GRIK
• Synonyms gene name
  • glutamate receptor, ionotropic, kainate 4
• Synonyms
  • GluK4
  • KA1
• GenBank acession
  • S67803
• Locus
  11q23.3
• Discovery year
  1993-07-29
• Entrez gene record
  2900
• RefSeq identity
  • NM_014619
• Classification
  • Glutamate ionotropic receptor kainate type subunits
• VEGA ID
  OTTHUMG00000048255
• Locus Specific Databases
  • LRG_1012

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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